Kara was born on the Planet Krypton and is the daughter of Alura and Zor-El. She had a happy childhood and admired and deeply loved her parents. Kara and her family were known to go visit numerous planets for family hoildays. However, Kara's life changed forever when the Planet Krypton was destroyed, her parents managed to save Kara and her baby cousin Kal-El, allowing them to escape the Planet's destruction and go to Planet Earth. Kara's parents instruct Kara to protect and raise Kal-El. However, when Kara escaped the Planet's destruction, the pod she was in went off course and for years she was stuck in the Phantom Zone. Later, the pod containing Kara managed to break free and she eventually made her way towards Earth only to learn Kal-El grew up and has already become Superman
Kara is sent to live with the Danvers family, close allies to Superman and they become her adoptive family consisting of Jeremiah, Eliza and Alex. Kara was forced to keep her powers a secret from the public and tried to grow up and have a normal life for herself. While Kara struggled to hide her powers and live on Earth, she came to adjust with the support of her adoptive family and developed a close relationship with Alex. However, Kara still deeply misses her parents, but still loves the Danvers for all they've done for her.
Winn Schott is Kara's best friend and former co-worker at CatCo Worldwide Media. Ever since Kara first arrived at CatCo, Winn instantly developed strong romantic feelings for her, but Kara remained unaware of them and only saw Winn as her best friend. Since she began working at CatCo, they developed a strong friendship, but Kara remained completely unaware of Winn's feelings as they grew stronger over the years. Although they do not end up together, they are fondly known as Winnara.
Adam Foster is the oldest son of Kara's boss, Cat Grant, and a brief love interest in the first season. Kara didn't immediately take to Adam, although she found him attractive, but his charming demeanor drew her in. While out on a date Bizarro swoops down and drags Kara away. Kara and Adam dated until Kara called off the relationship citing that she didn't have room for him in her life. Adam then leaves back to Opal City. The ship is fondly known as Kadam.
James Olsen was originally Kara's main love interest in the first season of the series; fondly known as KarOlsen. Kara was instantly attracted to James and they found a fast friendship form. With James being Clark's best friend, he already knew of Kara being Supergirl. When James' ex Lucy Lane returns an unsavory love triangle forms between the three. Kara decides to step out of the way and lets James and Lucy rekindle their old romance. By the end of the season James and Lucy are over and James and Kara decide to start something together. In the beginning of the second season although Kara and James attempt to start a relationship, Kara decides it's better they remain friends, as although she held strong feelings in the beginning, she no longer desires anything more between them.
Mon-El of Daxam
Mon-El was Kara's main love interest in the second season of the series; fondly known as KaraMel. In the beginning of the second season they start off on the wrong foot. Due to the bad blood between Kryptons and Daxams, the relationship between Kara and Mon-El is strained. Kara wants to train him to become a superhero like her and he fights her every step of the way until he finally decides that he can be, with Kara's help, a better person and superhero. Things quickly escalate between them going from colleagues to lovers. There's is a relationship frequently compared to that of star-crossed lovers. By the end of season two the two of them have been torn apart by Mon-El's need to leave the Earth or risk death.
The relationship never rekindles. In season three Mon-El returns but he is married to Imra Ardeen. Kara and he have some shared moments together but in the end he returns back to his life in the future as a member of the Legion of Superheroes and Kara moves on.
- In the first season, Kara's original main love interest was James Olsen.
- Kara has no actual love interest in the third season.
- In the comics, Kara's most notable love interest is Querl Dox, aka Brainiac 5. Their relationship history spans decades. Querl has only just been introduced into the show as a series regular for the fourth season.